best of luck Cellular Organization part 3Explore Cellular Organization Part 3 with detailed insights into cell structure, functions, and key concepts of life sciences. Perfect for CSIR NET, GATE, and competitive exams preparation 1 / 50A secretory protein with mutated signal peptide will most likely: A) Stay in cytosol B) Enter ER normally C) Go to mitochondria D) Be degraded by lysosome 2 / 50Which step is energy-dependent in vesicle fusion? A) Cargo recognition B) Vesicle budding C) Vesicle uncoating & SNARE zippering D) Glycosylation 3 / 50The protein โlaminโ belongs to which cytoskeletal family? A) Actin B) Microtubule C) Intermediate filament D) Septin 4 / 50Nuclear export requires: A) Exportin, Ran-GTP B) Importin, Ran-GDP C) Exportin, Ran-GDP D) KDEL receptor 5 / 50GPI anchors attach proteins to: A) Cytosolic face of membrane B) Extracellular face of membrane C) ER lumen D) Nuclear pore 6 / 50Which cytoskeletal filament is most resistant to detergents? A) Microtubules B) Microfilaments C) Intermediate filaments D) Actin filaments 7 / 50Which complex powers retrograde movement along microtubules? A) Kinesin B) Dynein C) Myosin II D) Arp2/3 8 / 50Which organelle is semi-autonomous but NOT fully independent? A) Nucleus B) Lysosome C) Mitochondria D) Golgi 9 / 50Lysosomal enzymes are active at: A) Neutral pH B) Alkaline pH C) Acidic pH (~5) D) All pH levels 10 / 50Nuclear pore complex size limit for passive diffusion is: A) <20 kDa B) <40 kDa C) <60 kDa D) <100 kDa 11 / 50The โcisternal maturation modelโ explains transport through: A) Endosomes B) Golgi apparatus C) Peroxisomes D) Lysosomes 12 / 50Which of the following statements about mitochondria is FALSE? A) Have circular DNA B) Can undergo fission and fusion C) Synthesize all of their proteins D) Contain ribosomes 13 / 50Signal recognition particle (SRP) functions in: A) Translation initiation B) Co-translational targeting to ER C) Endocytosis D) Nucleocytoplasmic transport 14 / 50Actin stress fibers are connected to ECM through: A) Desmosomes B) Focal adhesions C) Tight junctions D) Hemidesmosomes 15 / 50Which protein facilitates retrograde transport of proteins from Golgi to ER? A) COPII B) COPI C) Clathrin D) Dynamin 16 / 50Proteins degraded by proteasome are usually tagged with: A) SUMO B) Ubiquitin C) Phosphate D) Glycosyl group 17 / 50Calnexin/calreticulin cycle in ER is mainly for: A) Protein glycosylation B) Protein folding quality control C) Vesicle formation D) Ribosome binding 18 / 50Peroxisome biogenesis defect causes: A) Tay-Sachs disease B) Zellweger syndrome C) Gaucherโs disease D) Sickle cell anemia 19 / 50Phagocytosis is mainly carried out by: A) Epithelial cells B) Fibroblasts C) Macrophages & neutrophils D) Neurons 20 / 50A mutation in tubulin that prevents GTP hydrolysis would result in: A) Microtubule destabilization B) Excessive microtubule stability C) Actin filament collapse D) Loss of nuclear lamina 21 / 50Which of the following pathways is default if no signal is present? A) Secretion outside the cell B) Retention in ER C) Lysosome targeting D) Nuclear import 22 / 50COPI vesicles mediate transport from: A) Golgi โ ER B) ER โ Golgi C) Plasma membrane โ Endosome D) Golgi โ Lysosome 23 / 50Lysosomal storage diseases often arise due to defect in: A) ER retention signal B) Mannose-6-phosphate tagging C) Rab protein signaling D) Nuclear localization signal 24 / 50SNARE complex functions in: A) Vesicle fusion B) Vesicle budding C) Vesicle transport D) Cargo glycosylation 25 / 50Rab proteins function in: A) Vesicle tethering B) Vesicle budding C) Cargo recognition D) Vesicle acidification 26 / 50Chloroplast DNA resembles: A) Linear nuclear DNA B) Circular bacterial DNA C) Linear mitochondrial DNA D) RNA genome 27 / 50Rubisco enzyme is found in: A) Thylakoid lumen B) Thylakoid membrane C) Stroma D) Cytosol 28 / 50Protein import into mitochondria requires: A) TOM & TIM complexes B) Sec61 channel C) Peroxins D) SRP 29 / 50F1 particle of ATP synthase is located in: A) Mitochondrial matrix B) Intermembrane space C) Inner membrane (facing matrix) D) Cytosol 30 / 50Cardiolipin is found mainly in: A) Outer mitochondrial membrane B) Inner mitochondrial membrane C) ER D) Plasma membrane 31 / 50Which nucleolus sub-compartment is site of rRNA transcription? A) Dense fibrillar component B) Fibrillar center C) Granular component D) Nuclear pore 32 / 50Nuclear matrix primarily contains: A) rRNA B) Lamin proteins C) Ribosomal proteins D) Mitochondrial proteins 33 / 50Which RNA polymerase synthesizes tRNA in eukaryotes? A) RNA Pol I B) RNA Pol II C) RNA Pol III D) Mitochondrial RNA Pol 34 / 50Ran-GTP is required for: A) Nuclear import completion inside nucleus B) Nuclear export in cytoplasm C) Protein folding in ER D) Ribosome assembly in cytoplasm 35 / 50NLS is usually rich in A) Hydrophobic residues B) Acidic residues C) Basic residues (Lys, Arg) D) Proline-rich motifs 36 / 50Which cytoskeletal element is most important for nuclear lamina? A) Microtubule B) Actin filament C) Intermediate filament D) Septin filament 37 / 50Actin filament barbed (+) end grows by: A) ATP-actin addition B) GDP-actin addition C) GTP-tubulin addition D) ADP-actin only 38 / 50Which drug stabilizes microtubules? A) Nocodazole B) Colchicine C) Taxol D) Vinblastine 39 / 50Microtubule plus-end binding protein is: A) EB1 B) ฮณ-tubulin C) Pericentrin D) Actinin 40 / 50The nucleation of actin filaments is regulated by: A) Arp2/3 complex B) ฮณ-tubulin ring complex C) MAPs D) Tau proteins 41 / 50Glycosylation starts in: A) ER lumen B) Golgi cisternae C) Lysosome D) Cytoplasm 42 / 50Brefeldin A primarily disrupts: A) Retrograde transport B) Anterograde transport (ER โ Golgi) C) Clathrin uncoating D) ER protein glycosylation 43 / 50Mutation in dynamin protein would primarily block: A) Clathrin-mediated endocytosis B) COPI vesicle budding C) ER protein import D) Peroxisome protein import 44 / 50Which signal directs proteins to peroxisomes? A) KDEL B) SKL (at C-terminal) C) NLS D) M6P 45 / 50COPII vesicles mediate transport: A) Golgi โ ER B) ER โ Golgi C) Plasma membrane โ Golgi D) ER โ Lysosome 46 / 50Aquaporins allow movement of: A) Water only B) Water and ions C) Small hydrophobic molecules D) Water and COโ 47 / 50Which type of transport does Glucose uptake by GLUT4 follow? A) Simple diffusion B) Simple diffusion C) . Primary active transport D) Secondary active transport 48 / 50The Naโบ/Kโบ-ATPase pump exports: A) 3 Naโบ out, 2 Kโบ in B) 2 Naโบ out, 3 Kโบ in C) 3 Naโบ in, 2 Kโบ out D) 2 Naโบ out, 3 Kโบ in 49 / 50FRAP (Fluorescence Recovery After Photobleaching) is primarily used to study: A) Organelle pH B) Protein phosphorylation C) Lateral diffusion of membrane proteins D) Apoptosis 50 / 50Cholesterol in plasma membrane mainly functions to: A) Increase membrane fluidity at low temperature B) Decrease membrane fluidity at high temperature C) Both A & B D) Anchor membrane proteins Your score isThe average score is 57% LinkedIn Facebook VKontakte 0% Restart quiz Share this: Share on X (Opens in new window) X More Share on Facebook (Opens in new window) Facebook Share on Telegram (Opens in new window) Telegram Share on WhatsApp (Opens in new window) WhatsApp Like this:Like LoadingโฆDiscover more from rashirozgar.comSubscribe to get the latest posts sent to your email. Type your emailโฆ Subscribe Post navigationCellular Organization part 2 test CSIR NET Life Sciences 2026: Complete Syllabus & Exam Overview
Cellular Organization Part 3